Month: March 2020
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The liver buffer(s)
One of the things I noticed in studying metabolism and the overall functioning of the body, is how important the liver is. A lot of what we do and a lot of what we measure is influenced by the liver and its buffers. Understanding these buffers in conjunction with these measurements may help us a…
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The life-shortening effect of high-protein
Diets come in many forms and some are keen on high protein amounts. While I agree that can be tasty, I’ve come across some material that may put a different light on what that intake means to longevity. There are many aspects to protein and the different type of sources but I’m more interested in…
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Insulin Resistance
Research in the past and present has shown us that fat causes insulin resistance. With ketogenic diets becoming increasingly popular, many people fear for a potential negative effect by inducing this insulin resistance. It is true that insulin resistance does appear on low carb high fat diets such as the ketogenic diet but the context…
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Low ketone levels so I utilize them better?
One of the pervasive thoughts in the keto community is that when they measure lower levels of ketones, the longer they are on the ketogenic diet, that this is caused by a better utilization of the ketones in the body. This is an effect noticed over several months or even years. But is this true?…
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Immune cell modulation by the ketogenic diet
What follows is a list of research that shows how a ketogenic diet can have effect on the immune system. A lot of this research is done in non-human bodies or circumstances so none of it has been proven to be similar in humans. This is very important to know because mice and rats have…
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Berberine on low carb
I’ve recently came across 2 cases of people who reported elevated glucose and insulin on a low carb diet. Naturally that is alarming because if there is one thing that low carb does well for you, it is to keep glucose and insulin low. It started with a person who recently came to the r/ketoscience…
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Oxidized LDL
When looking at the risk calculators for cardiovascular disease, your risk of coronary atherosclerosis is calculated based on several factors. Today we already see that LDL alone doesn’t create much of a risk when using the industry top ranked tools. It looks like science has moved on while medical care and general public is still…
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Cholesterol or ketones, can we have both?
I wanted to know the relationship between and what drives production of cholesterol versus ketones. The simple reason being that 3-hydroxy-3-methylglutaryl Coa or HMG-Coa (HMG) is either reduced by HMG-Coa reductase (HMGr) into the pathway towards cholesterol or HMG-Coa lyase (HMGl) sets it on the pathway towards Acetoacetate. So 2 enzymes work on the same…
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