Tag: carnitine

• Raising skeletal muscle carnitine

  Carnitine is required to bring the longer chain fatty acids into the mitochondrial matrix where it can be further broken down to produce ATP.  Carnitine Palmitoil Transferase 1a (CPT1a) is a mitochondrial outer membrane bound protein that will take in an acyl-CoA and bind it to carnitine resulting in acyl-carnitine.   On a ketogenic diet (KD),…

  DesignedByNature

  7 April 2023

  Geen categorie

  ascorbic acid, carnitine, insulin, ketogenic diet, protein, salt, skeletal muscle, vitamin C

• The key to enhance performance on a high-fat diet

  There is a professor (Louise Burke) who looked at athlete performance extensively in elite race-walkers. Shamefully the high-fat community has criticized her and attacked her because the results that she came up with showed that when it comes to world class athletes, there is no performance benefit and more likely there is a slight decrease.…

  DesignedByNature

  22 January 2021

  Geen categorie

  carnitine, elite athletes, high-fat, insulin, ketogenic diet, Louise Burke, performance

• Why are mice bad at ketogenesis?

  Previously I collected different studies to see how the mice perform on ketogenesis. Despite having a diet that often consists of >90% fat they produce disappointingly low BHB levels. Without thinking much about it I just assumed they are bad at fat metabolism biased by thinking they are typical high carb eating animals so they…

  DesignedByNature

  1 October 2020

  Geen categorie

  carnitine, exercise, fat metabolism, ketogenesis, LCFA, liver, long chain fatty acids, MCFA, medium chain fatty acids, mice