Tag: insulin
-
Heat acclimation & ketogenic diet
What does heat acclimation do to ketogenesis or is there any effect of the ketogenic diet on heat acclimation that is different from a more common SAD diet? I recently have been exposed to a hot climate and observed some weight loss (sweating, appetite loss, higher cycling mileage, …) and what felt like a reduction…
-
Rebuttal of the Lipid Energy Model hypothesis
On the 20th of May 2022, the Lipid Energy Model (LEM) was published in an attempt to explain the drastic elevation seen in LDL-c amongst lean individuals who are on a high fat diet with low carbohydrates. The purpose of this rebuttal is to open up discussion on some aspects of the hypothesis so that…
-
The misunderstanding of endurance adaptation and how to train all muscle types together
There are plenty of articles that explain much more in detail the different muscle fiber types and how to train for endurance or how to build muscle so I won’t go into those details. What I do want to address is the issue with getting both trained at the same time. First, the problem with…
-
The key to enhance performance on a high-fat diet
There is a professor (Louise Burke) who looked at athlete performance extensively in elite race-walkers. Shamefully the high-fat community has criticized her and attacked her because the results that she came up with showed that when it comes to world class athletes, there is no performance benefit and more likely there is a slight decrease.…
-
Hepatic Glucose Metabolism
After writing about the liver buffers I wanted to understand a bit more on the regulation of gluconeogenesis and buildup of the resulting glucose as glycogen in the liver. I have also written about protein being a supply-driven process with the mechanism intended to increase liver glycogen storage. In order for that supply-driven mechanism to…
-
Linking the hepatic glycogen buffer with protein protection
As a short recap of my article on the liver buffer, insulin causes the build-up of glycogen in the liver. When I looked into protein and fructose, I touched the topic of protein protection for the first time. With this article I wanted to go a bit deeper into this aspect and do this by…
-
LMHR and the elevated LDL cholesterol
For those who don’t know, LMHR stands for Lean Mass Hyper Responder and refers to the lipid profile of people who achieve high LDL cholesterol, high HDL cholesterol and low triglycerides. Hyper responder refers to the high LDL that is achieved and lean mass because most of these people appear to have low body fat.…
-
The liver buffer(s)
One of the things I noticed in studying metabolism and the overall functioning of the body, is how important the liver is. A lot of what we do and a lot of what we measure is influenced by the liver and its buffers. Understanding these buffers in conjunction with these measurements may help us a…
-
Berberine on low carb
I’ve recently came across 2 cases of people who reported elevated glucose and insulin on a low carb diet. Naturally that is alarming because if there is one thing that low carb does well for you, it is to keep glucose and insulin low. It started with a person who recently came to the r/ketoscience…
-
Cholesterol or ketones, can we have both?
I wanted to know the relationship between and what drives production of cholesterol versus ketones. The simple reason being that 3-hydroxy-3-methylglutaryl Coa or HMG-Coa (HMG) is either reduced by HMG-Coa reductase (HMGr) into the pathway towards cholesterol or HMG-Coa lyase (HMGl) sets it on the pathway towards Acetoacetate. So 2 enzymes work on the same…
Designed By Nature 