Tag: LDL cholesterol
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LDL as part of the immune system
Not many people know that the LDL particles which are floating around in our body play an active role in our immune system. I know of the gram-negative bacteria being captured because their endotoxin, lipopolysaccharide (LPS) binds to LPS-binding protein (LBP) via HDL particles (a good reason to have high HDL) and then transfers it…
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Pathologic LDL cholesterol
Throughout all my investigations on the ins and outs of cholesterol, energy metabolism, diseases such as T2 diabetes, cancer, Alzheimer’s, ageing etc.. I learned a lot about the environment of which the circulating lipids can be seen as a proxy for it. In the low carb community, as people get leaner there is a tendency…
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The curious case of macrophages and LDL cholesterol uptake in the pathology of atherosclerosis
Recently I wrote an article exploring what could be at the root cause of atherosclerosis. After the publication a comment pointed to the macrophage and cholesterol not being discussed. I didn’t do this because the root cause brought me to a point before macrophage and LDL-cholesterol comes into the picture. But it got me thinking……
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LMHR and the elevated LDL cholesterol
For those who don’t know, LMHR stands for Lean Mass Hyper Responder and refers to the lipid profile of people who achieve high LDL cholesterol, high HDL cholesterol and low triglycerides. Hyper responder refers to the high LDL that is achieved and lean mass because most of these people appear to have low body fat.…
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