The fat storage system

Perhaps not a very sexy name but why name it something else than what it is? After studying the functioning of our lipoproteins for a good 2 years (and still not finished learning!), it has finally become clear what those lipoprotein are meant for. As complex as it may be, the end goal is reallyContinue reading “The fat storage system”

CETP

Read it carefully as it may help you assess your risk for cardiovascular disease! In my previous article comparing pathological versus physiological high LDL-C levels, one of the marked differences is that HDL-C goes down under the pathological situation versus up on the physiological case. This difference comes down to cholesterol ester transfer protein orContinue reading “CETP”

Cancer.. where to look for clues

I’ve been interested in cancer for quite a while. Even before I got affected, the complexity and the link with metabolism caught my attention. Despite digging up all the details of how cancer develops and works, I somehow never could find a distinct feature of a cancer cell. I could not find a single featureContinue reading “Cancer.. where to look for clues”

The curious case of macrophages and LDL cholesterol uptake in the pathology of atherosclerosis

Recently I wrote an article exploring what could be at the root cause of atherosclerosis. After the publication a comment pointed to the macrophage and cholesterol not being discussed. I didn’t do this because the root cause brought me to a point before macrophage and LDL-cholesterol comes into the picture. But it got me thinking…Continue reading “The curious case of macrophages and LDL cholesterol uptake in the pathology of atherosclerosis”

The cause of atherosclerosis is unknown… or is it?

Medical establishment considers a causal role for cholesterol. There has been a great deal of effort put into lowering cholesterol without significant effect on curing and preventing the disease. How come the failure is so big? Is it really THE cause? I’m especially concerned because my LDL level is >300mg/dL It turns out that theContinue reading “The cause of atherosclerosis is unknown… or is it?”

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