Tag: glucose

• The bigger picture on fat-adaptation

  A paradigm shift in understanding I’ve looked into various topics related to metabolism and what a high fat diet changes versus high carb. Topics such as heat production, weight management, ATP production, protein sparing, lactate, BHB, glycogen, starvation, evolution, bone health and collagen cross-links specifically, pyruvate etc.. have come together in a meaningful way. What…

  DesignedByNature

  27 September 2021

  Geen categorie

  advanced glycation end products, ATP, evolution, glucose, health, heat production, maillard reaction

• Fructose, the really bad guy

  I came across a couple of resources and started to appreciate how different fructose is from glucose. In the low carb community, carbohydrates are obviously avoided or at least high amounts of it as they are generally considered bad. I support this approach but when we zoom in on fructose we notice that it is…

  DesignedByNature

  3 May 2020

  Geen categorie

  appetite, cardiovascular disease, cholesterol, chronic kidney failure, cognitive decline, fructose, fruit, glucose, gout, hippocampus, hypertension, insulin resistance, NAFLD, obesity, overfeeding, satiety, sugar, uric acid, visceral fat

• Hepatic Glucose Metabolism

  After writing about the liver buffers I wanted to understand a bit more on the regulation of gluconeogenesis and buildup of the resulting glucose as glycogen in the liver. I have also written about protein being a supply-driven process with the mechanism intended to increase liver glycogen storage. In order for that supply-driven mechanism to…

  DesignedByNature

  29 April 2020

  Geen categorie

  cAMP, demand driven, G6P, G6Pase, glucagon, glucokinase, gluconeogenesis, glucose, glycogenesis, glycogenolysis, hepatic glycogen, incretin, insulin, liver buffer, PEPCK, protein, supply driven

• The liver buffer(s)

  

  One of the things I noticed in studying metabolism and the overall functioning of the body, is how important the liver is. A lot of what we do and a lot of what we measure is influenced by the liver and its buffers. Understanding these buffers in conjunction with these measurements may help us a…

  DesignedByNature

  30 March 2020

  Geen categorie

  ApoB, beta-hydroxybutyrate, BHB, buffer, cholesterol, fatty acids, glucagon, gluconeogenesis, glucose, glycogen, glycogenesis, glycogenolysis, GNG, insulin, ketogenesis, liver

• Insulin Resistance

  Research in the past and present has shown us that fat causes insulin resistance. With ketogenic diets becoming increasingly popular, many people fear for a potential negative effect by inducing this insulin resistance. It is true that insulin resistance does appear on low carb high fat diets such as the ketogenic diet but the context…

  DesignedByNature

  27 March 2020

  Geen categorie

  DAG, de novo lipogenesis, diacylglycerol, fructose, glucose, glucose sparing, GLUT2, GLUT4, IMCL, insulin resistance

• Berberine on low carb

  I’ve recently came across 2 cases of people who reported elevated glucose and insulin on a low carb diet. Naturally that is alarming because if there is one thing that low carb does well for you, it is to keep glucose and insulin low. It started with a person who recently came to the r/ketoscience…

  DesignedByNature

  7 March 2020

  Geen categorie

  berberine, glucagon, gluconeogenesis, glucose, insulin, ketogenic diet, kidneys, lactate