The speed of the TCA in the liver

In previous writings I have looked at the liver and also ketone production from different angles but now I want to zoom in a bit on the TCA cycle itself. Previous related writings: The liver buffer(s) Cholesterol or ketones Hepatic glucose metabolism Hepatic glycogen and protein protection In order to accumulate sufficient substrate for ketogenesis,Continue reading “The speed of the TCA in the liver”

Why are mice bad at ketogenesis?

Previously I collected different studies to see how the mice perform on ketogenesis. Despite having a diet that often consists of >90% fat they produce disappointingly low BHB levels. Without thinking much about it I just assumed they are bad at fat metabolism biased by thinking they are typical high carb eating animals so theyContinue reading “Why are mice bad at ketogenesis?”

The liver buffer(s)

One of the things I noticed in studying metabolism and the overall functioning of the body, is how important the liver is. A lot of what we do and a lot of what we measure is influenced by the liver and its buffers. Understanding these buffers in conjunction with these measurements may help us aContinue reading “The liver buffer(s)”

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