Author: DesignedByNature
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The misunderstanding and miscalculation of fat and carbohydrate oxidation rates
The formulas widely used to calculate fat oxidation (FATox) in grams per minute and carbohydrate oxidation (CHOox) in grams per minute are the following: FATox (g/min) = 1.67 x VO2 (L/min) – 1.67 x VCO2 (L/min) CHOox (g/min) = 4.55 x VCO2 (L/min) – 3.21 x VO2 (L/min) VO2 and VCO2 are placeholders for the…
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CKM – Part 4 – Energy Management
Please read the previous articles on my CKM use for more background. My second Sibio CKM sensor was meant to monitor 2 weeks of heavy endurance exercise. Trying to capture the stress of increased volume and adaptation to it. Unfortunately that testing came to a quick end because the sensor took the exit quite soon. …
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CKM – Part 3 – What have 14 days of monitoring showed me?
Be sure to look at part 1 and part 2 for some more background and earlier observations. Ketone levels The graph below shows the mean values across these 14 days minus the first day as I was too sick and didn’t find it representative of normal levels. Clearly the sleeping period shows very low ketones, around…
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CKM – Part 2 – Sickness
Day 2 and this CKM has already put my mind at work. What I’ll write down below is how I interpret the data, knowing my own history, and using all the scientific literature I’ve read so far. But I have to admit, being sick is a variable I don’t know much of how it influences metabolism.…
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Continuous Ketone Monitoring (CKM) – Part 1
I’m in the possession of a couple of CKM sensors so now it is time to run a number of experiments and also generally see what a CKM can teach me and how useful it is to have one on your arm. This article is a first by which I want to introduce more about…
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Raising skeletal muscle carnitine
Carnitine is required to bring the longer chain fatty acids into the mitochondrial matrix where it can be further broken down to produce ATP. Carnitine Palmitoil Transferase 1a (CPT1a) is a mitochondrial outer membrane bound protein that will take in an acyl-CoA and bind it to carnitine resulting in acyl-carnitine. On a ketogenic diet (KD),…
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LDL as part of the immune system
Not many people know that the LDL particles which are floating around in our body play an active role in our immune system. I know of the gram-negative bacteria being captured because their endotoxin, lipopolysaccharide (LPS) binds to LPS-binding protein (LBP) via HDL particles (a good reason to have high HDL) and then transfers it…
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Ketones support the failing heart and may help repair it
I noticed that in the past few years there is quite a bit of research coming out investigating the effect of beta-hydroxybutyrate on a failing heart. It seems that a failing heart somehow increases the production of ketones which it then consumes to support its function. As this is picking up attention in the scientific…
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Endurance training
My most favorite sport is cycling and being an enthusiast on understanding energy metabolism, there’s an interesting triangle to form with the field of ketosis and sport performance. I originally started with thinking there’s a performance benefit when combining eating low carb with endurance due to the higher level of fat burning achieved and possible…
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Heat acclimation & ketogenic diet
What does heat acclimation do to ketogenesis or is there any effect of the ketogenic diet on heat acclimation that is different from a more common SAD diet? I recently have been exposed to a hot climate and observed some weight loss (sweating, appetite loss, higher cycling mileage, …) and what felt like a reduction…