Author: DesignedByNature
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Xanthelasma
People may be affected by a fatty deposition in the eyelids. The effect is more easily seen in people who have elevated levels of cholesterol and is therefor sometimes used as a marker of hyperlipidemia. But I’m not interested in hyperlipidemia although I keep it in mind that lipid deposition is part of the pathology.…
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The misunderstanding of endurance adaptation and how to train all muscle types together
There are plenty of articles that explain much more in detail the different muscle fiber types and how to train for endurance or how to build muscle so I won’t go into those details. What I do want to address is the issue with getting both trained at the same time. First, the problem with…
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The bigger picture on fat-adaptation
A paradigm shift in understanding I’ve looked into various topics related to metabolism and what a high fat diet changes versus high carb. Topics such as heat production, weight management, ATP production, protein sparing, lactate, BHB, glycogen, starvation, evolution, bone health and collagen cross-links specifically, pyruvate etc.. have come together in a meaningful way. What…
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Bone health on a ketogenic diet
Pulling the final plug on attacks Attacks? I follow up on all published papers related to ketosis and although the execution may be done correctly and data may be generated correctly.. the circumstances are often specific and the conclusions are stretched beyond the scope of what the data is representing or can represent. All to…
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The speed of the TCA in the liver
In previous writings I have looked at the liver and also ketone production from different angles but now I want to zoom in a bit on the TCA cycle itself. Previous related writings: The liver buffer(s) Cholesterol or ketones Hepatic glucose metabolism Hepatic glycogen and protein protection In order to accumulate sufficient substrate for ketogenesis,…
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Insight into evolution
Where do we come from and where is it taking us? Lately I’ve been exposed to different, seemingly unrelated pieces of information. However putting them all on the table, a pattern started to emerge. Join me in a philosophical trip making sense out of evolution and what it could possibly have in storage for us.…
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The fat storage system
Perhaps not a very sexy name but why name it something else than what it is? After studying the functioning of our lipoproteins for a good 2 years (and still not finished learning!), it has finally become clear what those lipoprotein are meant for. As complex as it may be, the end goal is really…