Author: DesignedByNature
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Pathologic LDL cholesterol
Throughout all my investigations on the ins and outs of cholesterol, energy metabolism, diseases such as T2 diabetes, cancer, Alzheimer’s, ageing etc.. I learned a lot about the environment of which the circulating lipids can be seen as a proxy for it. In the low carb community, as people get leaner there is a tendency…
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The key to enhance performance on a high-fat diet
There is a professor (Louise Burke) who looked at athlete performance extensively in elite race-walkers. Shamefully the high-fat community has criticized her and attacked her because the results that she came up with showed that when it comes to world class athletes, there is no performance benefit and more likely there is a slight decrease.…
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Cancer.. where to look for clues
I’ve been interested in cancer for quite a while. Even before I got affected, the complexity and the link with metabolism caught my attention. Despite digging up all the details of how cancer develops and works, I somehow never could find a distinct feature of a cancer cell. I could not find a single feature…
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The curious case of macrophages and LDL cholesterol uptake in the pathology of atherosclerosis
Recently I wrote an article exploring what could be at the root cause of atherosclerosis. After the publication a comment pointed to the macrophage and cholesterol not being discussed. I didn’t do this because the root cause brought me to a point before macrophage and LDL-cholesterol comes into the picture. But it got me thinking……
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The cause of atherosclerosis is unknown… or is it?
Medical establishment considers a causal role for cholesterol. There has been a great deal of effort put into lowering cholesterol without significant effect on curing and preventing the disease. How come the failure is so big? Is it really THE cause? I’m especially concerned because my LDL level is >300mg/dL It turns out that the…
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The case for fat adaptation in endurance
– Pointing out the obvious – It is pretty obvious by now in sports is that if the body requires something then you need to give that in order to enhance performance. Be it vitamines, minerals, energy… whatever it needs to produce that wattage, make sure it doesn’t fall short to sustain the performance. Except…
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Curing Cancer
I have received a cancer diagnose last year. Thankfully my predating interest in metabolism already exposed me to lots of research material, including about cancer. I already collected material in the event I would ever get cancer. It may seem a bit ironic but we have a high chance being faced with it in our…