Prurigo Pigmentosa aka keto-rash

Prurigo Pigmentosa (PP) is a skin rash that can establish itself when people transition to a ketogenic diet. If you want to know how it looks like then you’ll find plenty of examples on Google. On our Reddit channel r/ketoscience we have published case reports and sometimes get people questioning about it. Obviously people whoContinue reading “Prurigo Pigmentosa aka keto-rash”

Hepatic Glucose Metabolism

After writing about the liver buffers I wanted to understand a bit more on the regulation of gluconeogenesis and buildup of the resulting glucose as glycogen in the liver. I have also written about protein being a supply-driven process with the mechanism intended to increase liver glycogen storage. In order for that supply-driven mechanism toContinue reading “Hepatic Glucose Metabolism”

Linking the hepatic glycogen buffer with protein protection

As a short recap of my article on the liver buffer, insulin causes the build-up of glycogen in the liver. When I looked into protein and fructose, I touched the topic of protein protection for the first time. With this article I wanted to go a bit deeper into this aspect and do this byContinue reading “Linking the hepatic glycogen buffer with protein protection”

LMHR and the elevated LDL cholesterol

For those who don’t know, LMHR stands for Lean Mass Hyper Responder and refers to the lipid profile of people who achieve high LDL cholesterol, high HDL cholesterol and low triglycerides. Hyper responder refers to the high LDL that is achieved and lean mass because most of these people appear to have low body fat.Continue reading “LMHR and the elevated LDL cholesterol”

Longevity (2a)

In the introduction on vaccination there were a couple of questions raised to delve deeper into. In this post we’ll have a look at the following question: Do vaccines get tested for safety in the same (rigorous) way as other drugs? So we need to look at how drugs are tested in general and thenContinue reading “Longevity (2a)”

The liver buffer(s)

One of the things I noticed in studying metabolism and the overall functioning of the body, is how important the liver is. A lot of what we do and a lot of what we measure is influenced by the liver and its buffers. Understanding these buffers in conjunction with these measurements may help us aContinue reading “The liver buffer(s)”

The life-shortening effect of high-protein

Diets come in many forms and some are keen on high protein amounts. While I agree that can be tasty, I’ve come across some material that may put a different light on what that intake means to longevity. There are many aspects to protein and the different type of sources but I’m more interested inContinue reading “The life-shortening effect of high-protein”

Insulin Resistance

Research in the past and present has shown us that fat causes insulin resistance. With ketogenic diets becoming increasingly popular, many people fear for a potential negative effect by inducing this insulin resistance. It is true that insulin resistance does appear on low carb high fat diets such as the ketogenic diet but the contextContinue reading “Insulin Resistance”

Low ketone levels so I utilize them better?

One of the pervasive thoughts in the keto community is that when they measure lower levels of ketones, the longer they are on the ketogenic diet, that this is caused by a better utilization of the ketones in the body. This is an effect noticed over several months or even years. But is this true?Continue reading “Low ketone levels so I utilize them better?”

Immune cell modulation by the ketogenic diet

What follows is a list of research that shows how a ketogenic diet can have effect on the immune system. A lot of this research is done in non-human bodies or circumstances so none of it has been proven to be similar in humans. This is very important to know because mice and rats haveContinue reading “Immune cell modulation by the ketogenic diet”

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